Vines: Sustainably Delivered to Skin

Wine is one of the largest crops in the Nyons region. After almost 20 years since the first documents were filed, the Nyons wine area was recognized by an AOC at the end of 2020. This makes it the last and the 22nd AOC in Côtes du Rhône.

A field of alternating vines and olive groves under a blue sky with mountains in the distance.
A typical landscape in the Nyons area with alternating vines and olive groves.

Wine pomace (or marc in French) is the collection of solid material remaining after the pressing of grapes for juice during the wine-making process. About 30% of pomace is crushed grape components, such as skins, pulp, seeds, and stems of the fruit. Grape pomace has traditionally been used to produce pomace brandy and grape-seed oil. It is mostly used as cattle feed or natural fertilizer today.

Around 70% of the phenolic compounds present in grapes remains in the grape pomace after the wine-making processing. Proscien’s patent-pending extraction and delivery technology enables us to efficiently utilize this by-product stream for cosmetic functions. ProActive™ Rosé is the fruition of this research. To maintain consistency, we have fixed partnership with a local winery. ProActive™ Rosé is derived from the same type of grape grown on the same piece of land.

Magenta juice pouring out of a barrel.
Separation of grape juice and pomace.

We pack in ProActive™ Rosé (INCI: Vitis Vinifera (Grape) Fruit Extract (and) Theobroma Cacao (Cocoa) Seed Butter) all the antioxidants of red wine and deliver them in a skin-available form. Extensive cell biology studies have demonstrated that ProActive™ Rosé is very effective in reducing hyperpigmentation caused by UV, acne, or hormones.

A bar chart showing B16F1 melanin content.
Reduce α-MSH (α-Melanocyte-Stimulating Hormone) stimulated melanin in B16F1 cells.
A bar chart showing Melan-a melanin content.
Reduce α-MSH (α-Melanocyte-Stimulating Hormone) stimulated melanin in Melan-a cells.
A bar chart showing melanin content.
Reduce solar UV stimulated melanin in normal human melanocytes (Fitzpatrick Type III/IV).